منابع مشابه
Sucralose, A Synthetic Organochlorine Sweetener: Overview of Biological Issues
Sucralose is a synthetic organochlorine sweetener (OC) that is a common ingredient in the world's food supply. Sucralose interacts with chemosensors in the alimentary tract that play a role in sweet taste sensation and hormone secretion. In rats, sucralose ingestion was shown to increase the expression of the efflux transporter P-glycoprotein (P-gp) and two cytochrome P-450 (CYP) isozymes in th...
متن کاملPhotochemical Fate of the Artificial Sweetener Sucralose in the Environment
.................................................................................................................................. iii ACKNOWLEDGMENTS ............................................................................................................. iv LIST OF TABLES .........................................................................................................................
متن کاملActivation of the sweet taste receptor, T1R3, by the artificial sweetener sucralose regulates the pulmonary endothelium
A hallmark of acute respiratory distress syndrome (ARDS) is pulmonary vascular permeability. In these settings, loss of barrier integrity is mediated by cell-contact disassembly and actin remodeling. Studies into molecular mechanisms responsible for improving microvascular barrier function are therefore vital in the development of therapeutic targets for reducing vascular permeability in ARDS. ...
متن کاملFemale rats show a bimodal preference response to the artificial sweetener sucralose.
The preference of female Sprague-Dawley rats for sucralose, a non-nutritive sweetener derived from sucrose, was evaluated in 23 h two-bottle tests with water or saccharin. Overall, the rats displayed weak or no preferences for sucralose (0.25-4 g/l) over water but strong preferences for saccharin (0.5-8 g/l) over water and saccharin (1 g/l) over sucralose (0.5 g/l). The rats also preferred a sa...
متن کاملEffect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.
The incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), play an important role in glucose homeostasis in both health and diabetes. In mice, sucralose, an artificial sweetener, stimulates GLP-1 release via sweet taste receptors on enteroendocrine cells. We studied blood glucose, plasma levels of insulin, GLP-1, and GIP, and gastric emptying ...
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ژورنال
عنوان ژورنال: Modern Applied Science
سال: 2008
ISSN: 1913-1852,1913-1844
DOI: 10.5539/mas.v2n3p13